名稱(chēng) | TP53 p.G389W Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10529 |
報(bào)價(jià) | ![]() |
特點(diǎn) | TP53 p.G389W Reference Standard |
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Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10529TP53 p.G389W Reference Standard 標(biāo)準(zhǔn)品

- 詳細(xì)內(nèi)容
CBP10529 | |
Format | Genomic DNA |
Description | TP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
Technical Data | |
DNA Change | c.1165G>T |
AA Change | p.G389W |
Mutation type | Missense_Mutation |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | ENST00000269305.4 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr17:7572944 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |